Key features
Overview
The Chemistry High-Throughput Experimentation has hree integrated modules including: a Powder Dosing Module for solid sample preparation, a Reaction Module for liquid sample preparation and reaction execution, and a LCMS (Liquid Chromatography Mass Spectrometry) Preparation Module which also includes rack storage. The Reaction and Powder Dosing Modules are contained within a glovebox, providing a dry, inert atmosphere under positive pressure nitrogen to allow for handling of oxygen-sensitive materials.
Reaction racks and rack-based consumables are loaded by the user to the rack store. Racks are transferred to the Reaction Preparation and Execution module, within the glovebox, via the automated antechamber. After dispensing of the solid samples into the required reaction vials, the racks are transferred to the Reaction Execution module for liquid dispensing before being lidded, clamped and the reaction is performed. After reaction, the racks are transferred to the LCMS Preparation Module for dry-down.
Processing each reaction rack involves dosing powders to each vial on the Powder Dosing Module, dosing liquid from the source vials within the Reaction Module, and then sealing, heating and stirring independently.