Custom project

Combinatorial chemistry cleaver and replicator

A Labman well-plate resin cleaver and replicator for a large USA-based firm. Including remote log-in, plate lidding, bar code tracking and more...
Labman custom system: Combinatorial chemistry cleaver and replicator

Key features

Target Plates180 final target plates
Tip Sets60 tip sets
Source Blocks60 source blocks
Cleave & Replicate Blocks4 hours to cleave and replicate 24 blocks into 3 daughters
Easy Integration into Lab2.3m x 1.5m footprint
Clean, Lab-Quality ComponentsPFTE and stainless steel components


System Overview.

The Labman well plate resin cleaver and replicator is installed in America. Source deep well plates are loaded into the stacker whereupon they are opened, the sample cleaved from the resin with trifluoroacetic acid, then they are washed and replicated into standard 96 well plates. Additional reagents include acetonitrile, DMSO, methanol and isopropanol. The system includes remote log on and control, plate lidding and de-lidding, bar code tracking, foil pierce station, reagent level controls and a tip washing / exchange methodology. PFTE and stainless steel components help protect the mechanics against the aggressive acid. Protocols may be developed offline.



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